V. Stanzl ,  L. M. Zopf ,  S. H. Geyer ,  N. Swiadek ,  J. Zinnanti ,  P. Slezak ,  W. J. Weninger ,  A. Walter ,  K. Bühler (2019)

An Open-Source Pipeline for Correlation and Visualization of Multi-Modal Multi-Scale Imaging Data in Tumor Vascularization.

Wo ist die Publikation erschienen?

EMIM 2019 (abstract and poster)


Activating angiogenesis is one of the main indicators of cancer supporting rapid tumor growth and metastasis. Current treatment strategies aim at inhibiting tumor neo-angiogenesis, but tumor vessels are disorganized, leaky and dysfunctional. To understand how tumors instruct the formation and maintenance of blood vessels, we apply ultra-high field MRI, µCT and HREM to a xenograft mouse model and correlate the tumor vessels. The proposed open source visualization pipeline supports the analysis of angiogenesis by depicting the different vessels and anatomical context in a single model.